Should you Actually Care About Poop Health?

Have you ever thought that your poop is a mirror of your health? Here is a very interesting and informative article by mc schraefel, Ph.D and Krista Scott-Dixon, Ph.D.
The source: PercisionNutrition

From smiling poo emojis, to poop cafes, to turd charts that go viral, excrement is having a moment. But for many, the question remains: Should you actually care about poop health?
Our answer: Yes! Bowel movements can either signal that you’re doing great, or suggest health challenges before other symptoms arise. In this article, 6 things to pay attention to when it comes to your poo.
Your poo can say a lot about you.
Good-looking poop can indicate that your health and fitness is where it should be. For instance, it can tell you:

  • Your core muscles are strong.
  • Your gastrointestinal system is pumping nicely.
  • You’re getting plenty of fiber and other nutrients.
  • Your hormones are happy.
  • You aren’t overly stressed.

Your intestinal flora are balanced and thriving.
If your poo isn’t looking so great, it might tell you something important. For instance, less-than-stellar poo might say things like:

  • You may need to improve your nutrition.
  • You may be stressed and anxious.
  • You may need to drink more water.
  • You may have a food intolerance.
  • You may need more daily activity to help things move along better.
  • You may have a health issue that’s standing between you and the way you want to look and feel.

Your poo is a clue.
In Precision Nutrition Coaching, we don’t talk doody on the first date. But we do get to it eventually.
Digestive health says a lot about overall health.
If you’re feeling low-energy or sluggish; if you’re having trouble losing weight, feeling good, and/or getting in shape, your poo can help us get to the, ahem, bottom of things. (Sorry.)
First things first: Take a look at your poo.
- Make like a toddler and peek into the toilet.
- Check out the chart below and answer honestly:
- What is your poo quality like most of the time?

As you can see, type 4 poo is what you want to shoot for. Types 3 and 5 are reasonably good, while types 1, 2, 6, and 7 shout, “Needs improvement”.
Here are some questions to ask yourself:

  • How often are you going?
  • One to three bowel movements per day = ideal.
  • How does it feel?

Assuming you didn’t eat spicy street meat last night, bowel movements should be quick and painless. They shouldn’t require straining, a panicked run to the toilet, or sitting long enough to do the entire New York Times crossword.
What color is it?
Healthy poo is brown. The color comes from bile, which emulsifies dietary fat and helps us digest it. However, you may notice some normal day-to-day changes, like green poo after eating leafy greens, or red poo after eating beets.
How does it smell?
It’s never going to smell like roses, but extremely foul-smelling poo can point to underlying issues.
Does it sink or float?
Healthy poo may do either, but this offers hints as to the fat (float) to fiber (sink) ratio of your diet.
Of course, poo will vary a bit from day to day. One day of rabbit raisins or post-burrito shenanigans doesn’t mean there’s something horribly wrong with you.
You’re looking for the long-term trend — what’s common for you.

Taking the answers to all of these questions into account, you should have a good sense for where your poo falls on the health scale.
6 things your poo could be trying to tell you.
If your poo is zipping along just fine, as sleek as an otter and as regular as a Swiss watch, great.
If your poo could use a little… im-poo-vement (sorry again)… read on. It might be a cry for help.
The good news:
Many of these issues can be fixed (or at least improved) with better nutrition and more consistent health habits.
Message #1.
Your gut could be working better than it is.
Most of the GI tract is a muscular tube that pushes food through with peristalsis, rhythmic muscular contractions that work much like squeezing a tube of toothpaste.
As food goes through this tube, it’s mushed up and chemically broken down so that we can absorb nutrients. And, of course, once we’re done with it, we excrete it as poo (or feces, if you would prefer the grown-up word).
When your gut is healthy and everything is working properly, it produces healthy poo. Problem poo can signal that something is interfering with your gut’s normal operating procedures.
Beyond factors like your microbial balance and your diet (which we’ll cover in a minute), things that could cause gut dysfunction include:

  • nutrient deficiencies
  • autonomic nervous system (ANS) problems
  • immune problems
  • hormone imbalance
  • blood sugar irregularities
  • medical procedures such as bariatric surgery
  • disrupted circadian rhythm (e.g. jet lag, shift work)
  • medications like antibiotics and painkillers
  • aging
  • chronic diseases like Crohn’s and colitis

Why you should care
Because of how the enteric nervous system — your gastrointestinal “brain” — works, you often don’t feel pain when things are wrong in your gut.
(Though sometimes you may feel too much pain. This is known as “visceral hyper-sensitivity”, and it’s what folks with inflammatory bowel disease, or IBD, often experience.)
So, you can’t always feel gut pain, and maybe you’re used to “problem poo”.
You may think: If it ain’t broke, why fix it?
Well, many of the root problems in the list above are serious. At least a few of them are worth a call to your doctor.
In addition, the gut bone is connected to the brain bone. Your enteric nervous system constantly communicates with your central and autonomic nervous systems, which controls every voluntary and involuntary function of the body.
Emerging research suggests: The state of the GI tract affects the quality of this messaging from gut to brain.
So if your gut is unhappy, you might notice psychological and cognitive problems such as:

  • brain fog
  • anxiety, depression or other mood disorders
  • ADD/ADHD

You may also have other physical problems such as:

  • trouble controlling your weight
  • asthma and allergies
  • autoimmune disorders
  • skin conditions (e.g. rashes, acne)
  • arthritis / joint inflammation
  • heart disease
  • neurodegenerative disease
  • narcolepsy or other sleep disorders
  • migraines
  • kidney problems

These, obviously, will make it pretty hard to look and feel your best.
How to fix it
Choose whole, minimally processed foods like fruit, vegetables, and fresh meat — the richest sources of the nutrients your gut needs.
Practice eating slowly and mindfully, and tune into your physical hunger and satiety cues.
This will help take care of any deficiencies and ensure that your food doesn’t move too quickly through the GI tract, which can hinder nutrient absorption.
And if you’re truly concerned (or even think you might be truly concerned), it’s never a bad thing to sync up with your doctor and make sure there aren’t more serious problems that need addressing.

Message #2.
Your microbiotic balance is messed up.
Our microbiome is the vast, complex and rich ecosystem of commensal, or friendly, bacteria (and sometimes fungi) that live on and around us.
These little critters are everywhere: in our noses, our mouths, our skin, and in our gastrointestinal (GI) tract.
The bacteria in the gut — or the gut flora — help us digest and absorb food by breaking down carbohydrates, and by helping to create digestive enzymes.
Healthy poo is a sign that your bacteria are doing their job. Problem poo may indicate your gut bacteria populations have taken a hit. Gut bacteria can be affected by things like travel, a change in diet, or a course of antibiotics.
Why you should care
The gut flora have many jobs that go beyond digestion. These can include:
Protecting the body from pathogens
Boosting the immune system
Making certain vitamins, such as biotin (vitamin B7), folate (vitamin B9), and vitamin K
And, of course, let’s not forget that struggling gut flora means struggling gut function — so see above for a long list of health consequences in that department.
How to fix it
You want lots of gut critters, and lots of different types.
To nourish the bacteria you already have, eat foods that contain prebiotics — starches that help keep good microbes alive. These include things like:

  • beans and legumes
  • fruits
  • whole grains
  • starchy vegetables and tubers (such as potatoes, sweet potatoes, taro/cassava, yuca, etc.)

Experiment to find which foods work for you, as some types of fermentable carbohydrates may bother you (see Message 3 below).
To add to your GI tract’s microbiome, consider eating more foods that contain probiotics (another word for good bacteria). These include yogurt or kefir, mold-enhanced cheese, and fermented products like sauerkraut, pickles, and kimchi.
You can increase or support the diversity of your gut’s microbiome by eating a wide variety of fresh, whole, minimally processed foods, which naturally contain more bacteria than processed foods. Organic foods may provide even more diversity since they haven’t been treated with bacteria-killing pesticides.
Also consider eating an occasional garden-picked fruit or veggie without washing it (assuming nothing’s been using your garden as a litter box).
Finally, avoid overusing antibiotics, which kill all the bacteria in your system, not just the bad stuff. (But when you need a round of the meds, by all means — take them!).

Message #3.
Your diet isn’t working for you.
No surprise — your poo is a reflection of what you eat. If you have problem poo, then your diet could be compromising your GI function in a few ways.
Fiber
Poo types 1 and 2 signal constipation, which may mean that you aren’t getting enough fiber.
We need fiber for proper GI function and healthy poo because:
Fiber helps feed gut bacteria and move food through the gut.
Fiber binds to fats, and helps excrete some types of hormones (such as estrogens).
Fiber ferments in the large intestine, creating short chain fatty acids, an important source of fuel for the body.
Fiber adds bulk and improves regularity, reducing our exposure to potentially dangerous compounds.
Finally, the breakdown of fiber regulates pH balance, promoting the optimal environment for beneficial bacteria.
Food sensitivities
Some people are more sensitive to certain foods that others. If you have a food sensitivity, you might experience symptoms ranging from constipation to urgent bathroom visits.
No two people are exactly alike. What works for one person may not work for another. (Maybe you’ve heard lentils are a superfood, but if they send your tummy into a tsunami, they’re probably not good for you.)
Four common offenders include:

  • lectins (found in seeds, grains, legumes and nuts);
  • gluten and related proteins (found in grains);
  • casein, lactose and immunoglobulins in dairy; and
  • fructose (aka fruit sugars) along with other types of sugars and starches (such as oligosaccharides or sugar alcohols) that many people struggle to digest.

Processed foods
Some people are sensitive to ingredients often found in processed foods, such as added sugars, refined grains, and food preservatives/additives such as MSG.
How to fix it
Try keeping a food diary that tracks what you eat along with any symptoms you notice. Sometimes, food sensitivities don’t show up right away; they might take a few hours or even a day or two.
So, recording what you eat and how you feel for a week or two can show you patterns that you might otherwise miss.
If you’re eating foods that don’t agree with you, or if you are missing key nutrients, your bowel movements (or lack thereof) will reflect that.
Eat more whole, fresh fruits, vegetables, and whole grains. Notice which ones digest best for you, and keep those on the menu.
Cut down on processed food when possible.
If you suspect you might have a food sensitivity, talk to your doctor or nutrition coach about an elimination diet.

Message #4.
You’re dehydrated.
If your poo is small and hard, you may assume you need more fiber — but it may actually mean you‘re not getting enough water.
Why you should care
Water helps move waste through and keep gut flora healthy. If you’re not getting enough water, these two things won’t happen effectively.
If the gut needs water and isn’t getting it, it’ll pull that water from elsewhere to get the job done, which can compromise other systems. For instance, you might get muscle cramping or a dry mouth.
How to fix it
Drink more water, especially during and after workouts.
Look at your overall beverage consumption. How much of that is juice, soda, caffeinated drinks, and/or alcohol? Could you substitute water for those things instead, or at least alternate glasses of water with each beer or coffee?

Message #5.
You’re too stressed
Remember, your GI tract is connected to your central nervous system. Your upstairs brain and your “gut brain” talk to each other.
When you’re stressed (or afraid, or anxious, or rushed, or overwhelmed), your brain and gut know, and your digestion slows down.
Ever had the experience of not being able to eat when you’re feeling especially anxious? That’s because blood flow and enzyme production in the gut are limited during stress.
Your GI tract may slow down so that your body can focus on dealing with what it sees as a threat, so you may find yourself constipated, bloated, and dealing with indigestion.
Or your body may follow an “everyone out of the pool” policy, and things may run right through you.
Bottom line: If you’re constipated or frequently rushing to the toilet, your stress levels may be past the area of “good stress” and into unhealthy territory.
Why you should care
If your poo is telling you you’re too stressed, you might also be dealing with:

  • anxiety
  • anger
  • grief, loss, sadness
  • depression
  • trouble focusing
  • headaches
  • fatigue
  • sleep problems
  • low sex drive, poor fertility, and/or a disrupted menstrual cycle (if you’re female)

How to fix it
Take stress seriously. Think about how to take care of you. (You’re worth it, after all.)
Make de-stressing a regular part of your routine.
Try stuff like:

  • getting outside for a walk… or just outside in general;
  • getting some sun and fresh air;
  • listening to relaxing music;
  • meditating and other mindfulness practices;
  • getting a massage;
  • taking a hot bath;
  • taking a few really good deep breaths;
  • laughing;
  • snuggling a loved one or pet;
  • yoga, gentle mobility, and/or slow stretching exercises;
  • gentle swimming or water immersion (such as a hot tub);
  • relaxing in a sauna;
  • having sex (see? who says nutrition coaching is boring?);
  • physically playing (yes, playing… remember that?).

Message #6.
Your workout routine isn’t working for you
If you’re not moving your body enough — or working out too intensely — your poo may suffer.
Physical activity keeps systems both outside and inside the body in shape.
On the one hand, a sedentary lifestyle can lead to constipation (use it or lose it, as they say — and it goes for your bowels, too).
On the other hand, overtraining can cause major stress on the body, leading to a too-stressed state and loose or watery stool (see above).
So you’re looking for the right balance of movement and recovery.
Why you should care
Sedentary living has plenty of problems aside from causing us to put on extra fat, or lose bone and muscle mass. It can also make us constipated. Being constipated is no fun.
Conversely, over-exercise can also damage your gut.
At rest, the gut receives over half of all organ blood flow, but during exercise, blood flow to the gut can drop to less than 20 percent of this resting value. Lack of blood flow to the gut during digestion can lead to increased intestinal permeability (aka leaky gut).
Many endurance athletes in particular also report the “runner’s trots”, aka sudden bouts of diarrhea while exercising.
Ironically, both endurance exercisers and people with heart failure are susceptible to leaky gut syndrome. In each case (though for entirely different reasons), not enough blood is making it to the gut.
How to fix it
Find ways to move your body that you truly enjoy, so “exercise” doesn’t feel like a slog. Walking the dog? Dance party with the kids? Yoga? Cleaning out the attic? Everyone has their thing. You do you.
(Krista’s 90-year-old grandma, a diligent daily walker all her life, insists, “A good walk cleans you out!”)
If you suspect you’re overtraining, keep a journal for a couple weeks. For instance:
Are you noticing other overtraining symptoms, like muscle aches or fatigue?
How do you feel during and in between workouts when you moderate?
How does it feel to get some active recovery time, like an easy swim or playing on the playground with your nephews?
Once you find your ideal balance, your poo should improve.

What to do next:
Some tips from Precision Nutrition.
If you think your poo (and your habits) could use a makeover, here are some simple things to try.
Turn around and look down.
To make the best use of your poo as a health-assessment tool, get it the habit of checking its quality on a daily basis.
If you’re new to this practice, start with a simple test using hydration, probably the easiest variable to manipulate:
At the next opportunity, make a note of the quality of your poo.
For the next seven days, increase your daily water intake while making no other changes to your intake.
Document your poo for each of these seven days. How did it change?
The same process can be used to fine-tune other aspects of your lifestyle, such as whole-food consumption and exercise, which may take a bit longer to cause changes in your poo.
The key idea here: Consistency.
To close the loop on your poop, it’s crucial to assess poo regularly and closely adhere to any adjustments you make in an effort to improve the quality.
Consider using a bowel movement tracking app to make regular assessments easier.
Take steps to keep your bacteria balanced.
The ratio of various bacteria that make up your microbiome can be kept well by certain healthy habits.
Follow basic food hygiene.
Wash your hands often, wash produce, keep your kitchen clean.
But don’t go scorched-earth. Regular, non-antibacterial soap and water are usually fine.
Eat a wide variety of produce.
Diversity in your diet means diversity in your nutrient intake and microbiome, so cast a wide net.
Try adding cultured and fermented foods to your diet.
This may include foods like:

  • fermented dairy such as yogurt, kefir, quark and skyr
  • fermented non-dairy such as almond or coconut milk yogurt
  • sauerkraut
  • kimchi and other Korean-style pickled vegetables (which are traditionally fermented rather than brined)
  • traditionally made miso, tempeh, and tofu, if you can find it

You may also consider a probiotic supplement. In North America, look for brands with the Good Manufacturing Process (GMP) sticker.
Eat slowly
Take your time to taste your food and notice how it makes you feel.
Slowing down will help your GI tract do its job (it hates to be rushed). It’ll help you eat the right amount for your body.
Paying attention to how your food makes you feel can tip you off to any food intolerances.
All of these help you maintain a healthy weight, healthy gut function, and healthy poo.
Talk to your doctor or nutrition coach about an elimination diet if you’re concerned about a food sensitivity, allergy, or intolerance.
Stay hydrated.
We need water to move things through our GI tract.
Drink up — especially on hot days and when you’re active.
Manage your stress
Too much stress can harm your health.
If stress or anxiety are either plugging you up or opening the sluice gates, try some stress management techniques and improve the quality of your sleep.
Give yourself time to go to the bathroom. Respect your body’s needs; if you have to evacuate your colon, do it.
Grow a garden and/or hang out at a farm.
If you live in a city, try joining a community garden project. If you can, drop by a farm occasionally — buy some fresh foods, get a little soil under your fingernails.
Being exposed to beneficial soil bacteria (such as Mycobacterium vaccae, which may even act as an antidepressant and immune system booster) can help diversify your microbiome.
As a plus, a little fresh air and time amongst plants can help decrease stress.
Know when to go to the doc.
If you notice red in your stool that isn’t from red gummi bears or beets, talk to your doctor.
While the presence of blood (which can be red or black) can be relatively benign (such as hemorrhoids), it can also be serious (such as colon cancer).
One look at your poo is not a complete health assessment. That said, it can tip you off about possible health concerns, where early detection matters.
Don’t try to diagnose on your own: if something strange is going on with your poo, talk to your doctor.
If you’re curious, get your microbiome tested.
Thanks to modern science, you can now learn more about your own unique microbiome. Through programs like uBiome you can get your microbiome tested through an online kit.
Bear in mind that there isn’t an industry standard in place yet. We still don’t know what the “best” balance of microbiota is. However, a test can tell you the basics, such as how diverse your internal ecosystem is.
Finally, if you think you need some extra support — whether it’s diet, stress management, or movement — remember that your friends at Precision Nutrition are always here to help.
We care about you… and your poo!

References
Ahmed, Z., Wang, Y., Ahmad, A., Khan, S. T., Nisa, M., Ahmad, H., & Afreen, A. (2013). Kefir and health: a contemporary perspective. Critical Reviews in Food Science and Nutrition, 53(5), 422–34. http://doi.org/10.1080/10408398.2010.540360
Asher, G., & Sassone-Corsi, P. (2015). Time for food: The intimate interplay between nutrition, metabolism, and the circadian clock. Cell, 161(1). http://doi.org/10.1016/j.cell.2015.03.015
Beek AP, Emous M, Laville M, Tack J. Dumping syndrome after esophageal, gastric or bariatric surgery: pathophysiology, diagnosis, and management. Obesity Reviews. 2016 Jan 1.
Berg P, McCallum R. Dumping syndrome: a review of the current concepts of pathophysiology, diagnosis, and treatment. Digestive diseases and sciences. 2016 Jan 1;61(1):11-8.
Burcelin, R. (2016). Gut microbiota and immune crosstalk in metabolic disease. Molecular Metabolism, 5(9), 771–81. http://doi.org/10.1016/j.molmet.2016.05.016
Burton-Freeman, B. (2000). Dietary fiber and energy regulation. The Journal of Nutrition, 130(2S Suppl), 272S–275S. Retrieved from
http://www.ncbi.nlm.nih.gov/pubmed/10721886
Butov DA, Efremenko YV, Prihoda ND, Zaitzeva SI, Yurchenko LV, Sokolenko NI, Butova TS, Stepanenko AL, Kutsyna GA, Jirathitikal V, Bourinbaiar AS. Randomized, placebo-controlled Phase II trial of heat-killed Mycobacterium vaccae (Immodulon batch) formulated as an oral pill (V7). Immunotherapy. 2013 Oct;5(10):1047-54. doi: 10.2217/imt.13.110. PubMed PMID: 24088075.
Cananzi FC, Mudan S, Dunne M, Belonwu N, Dalgleish AG. Long-term survival and outcome of patients originally given Mycobacterium vaccae for metastatic malignant melanoma. Human Vaccines & Immunotherapeutics. 2013;9(11):2427-2433. doi:10.4161/hv.25618.
Cani, P. D., & Knauf, C. (2016). How gut microbes talk to organs: The role of endocrine and nervous routes. Molecular Metabolism, 5(9), 743–52. http://doi.org/10.1016/j.molmet.2016.05.011
Davenport ER, Mizrahi-Man O, Michelini K, Barreiro LB, Ober C, Gilad Y. Seasonal Variation in Human Gut Microbiome Composition. Quintana-Murci L, ed. PLoS ONE. 2014;9(3):e90731. doi:10.1371/journal.pone.0090731.
David, L. A., Materna, A. C., Friedman, J., Campos-Baptista, M. I., Blackburn, M. C., Perrotta, A., … Alm, E. J. (2014). Host lifestyle affects human microbiota on daily timescales. Genome Biology, 15(7), R89. http://doi.org/10.1186/gb-2014-15-7-r89
Diaz-Gerevini, G. T., Repossi, G., Dain, A., Tarres, M. C., Das, U. N., & Eynard, A. R. (2016). Beneficial action of resveratrol: How and why? Nutrition, 32(2), 174–178. http://doi.org/10.1016/j.nut.2015.08.017
Dinan, T. G., & Cryan, J. F. (2015). The impact of gut microbiota on brain and behaviour: implications for psychiatry. Current Opinion in Clinical Nutrition and Metabolic Care, 18(6), 552–8. http://doi.org/10.1097/MCO.0000000000000221
Dinan, T. G., & Cryan, J. F. (2016). Gut Instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration. The Journal of Physiology. http://doi.org/10.1113/JP273106
Drell T, Larionova A, Voor T, Simm J, Julge K, Heilman K, Tillmann V, Štšepetova J, Sepp E. Differences in Gut Microbiota Between Atopic and Healthy Children. Curr Microbiol. 2015 Aug;71(2):177-83. doi: 10.1007/s00284-015-0815-9. Epub 2015 Apr 14.
Ericsson, K. A., Krampe, R. T., & Tesch-Römer, C. (1993). The role of deliberate practice in the acquisition of expert performance. Psychological Review, 100(3), 363–406. http://doi.org/10.1037/0033-295X.100.3.363
Falony G, et al. Population-level analysis of gut microbiome variation. Science. 2016 Apr 29;352(6285):560-4. doi: 10.1126/science.aad3503. Epub 2016 Apr 28.
Felice, V. D., Moloney, R. D., Cryan, J. F., Dinan, T. G., & O’Mahony, S. M. (2015). Visceral Pain and Psychiatric Disorders. Modern Trends in Pharmacopsychiatry, 30, 103–19. http://doi.org/10.1159/000435936
Furness, J. B., Callaghan, B. P., Rivera, L. R., & Cho, H.-J. (2014). The Enteric Nervous System and Gastrointestinal Innervation: Integrated Local and Central Control (pp. 39–71). http://doi.org/10.1007/978-1-4939-0897-4_3
Furness, J. B., Rivera, L. R., Cho, H.-J., Bravo, D. M., & Callaghan, B. (2013). The gut as a sensory organ. Nature Reviews Gastroenterology & Hepatology, 1010(1212), 729–740. http://doi.org/10.1038/nrgastro.2013.180
Gilbert JA, Alverdy J. Stool consistency as a major confounding factor affecting microbiota composition: an ignored variable? Gut. 2016 Jan;65(1):1-2. doi: 10.1136/gutjnl-2015-310043. Epub 2015 Jul 17.
Goffredo, M., Mass, K., Parks, E. J., Wagner, D. A., McClure, E. A., Graf, J., … Santoro, N. (2016). Role of Gut Microbiota and Short Chain Fatty Acids in Modulating Energy Harvest and Fat Partitioning in Youth. The Journal of Clinical Endocrinology and Metabolism, jc20161797. http://doi.org/10.1210/jc.2016-1797
Gururajan, A., Clarke, G., Dinan, T. G., & Cryan, J. F. (2016). Molecular biomarkers of depression. Neuroscience and Biobehavioral Reviews, 64, 101–33. http://doi.org/10.1016/j.neubiorev.2016.02.011
Harakeh, S. M., Khan, I., Kumosani, T., Barbour, E., Almasaudi, S. B., Bahijri, S. M., … Azhar, E. I. (2016). Gut Microbiota: A Contributing Factor to Obesity. Frontiers in Cellular and Infection Microbiology, 6, 95. http://doi.org/10.3389/fcimb.2016.00095
Harskamp CT, Armstrong AW. Immunology of atopic dermatitis: novel insights into mechanisms and immunomodulatory therapies. Semin Cutan Med Surg. 2013 Sep;32(3):132-9.
Heo, J., Seo, M., Park, H., Lee, W. K., Guan, L. L., Yoon, J., … Kim, H. (n.d.). Gut microbiota Modulated by Probiotics and Garcinia cambogia Extract Correlate with Weight Gain and Adipocyte Sizes in High Fat-Fed Mice. Scientific Reports, 6, 33566. http://doi.org/10.1038/srep33566
Hoban, A. E., Stilling, R. M., Ryan, F. J., Shanahan, F., Dinan, T. G., Claesson, M. J., … Cryan, J. F. (2016). Regulation of prefrontal cortex myelination by the microbiota. Translational Psychiatry, 6, e774. http://doi.org/10.1038/tp.2016.42
Ihana-Sugiyama N, Nagata N, Yamamoto-Honda R, et al. Constipation, hard stools, fecal urgency, and incomplete evacuation, but not diarrhea is associated with diabetes and its related factors. World Journal of Gastroenterology. 2016;22(11):3252-3260. doi:10.3748/wjg.v22.i11.3252.
Kelly, J. R., Borre, Y., O’ Brien, C., Patterson, E., El Aidy, S., Deane, J., … Dinan, T. G. (2016). Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat. Journal of Psychiatric Research, 82, 109–18. http://doi.org/10.1016/j.jpsychires.2016.07.019
Kelly, J. R., Clarke, G., Cryan, J. F., & Dinan, T. G. (2016). Brain-gut-microbiota axis: challenges for translation in psychiatry. Annals of Epidemiology, 26(5), 366–72. http://doi.org/10.1016/j.annepidem.2016.02.008
Koecher KJ, Thomas W, Slavin JL. Healthy subjects experience bowel changes on enteral diets: addition of a fiber blend attenuates stool weight and gut bacteria decreases without changes in gas. JPEN J Parenter Enteral Nutr. 2015 Mar;39(3):337-43. doi: 10.1177/0148607113510523. Epub 2013 Nov 14.
Kong LC, Tap J, Aron-Wisnewsky J, Pelloux V, Basdevant A, Bouillot JL, Zucker
JD, Doré J, Clément K. Gut microbiota after gastric bypass in human obesity:
increased richness and associations of bacterial genera with adipose tissue
genes. Am J Clin Nutr. 2013 Jul;98(1):16-24. doi: 10.3945/ajcn.113.058743. Epub
2013 May 29.
Konturek PC, Haziri D, Brzozowski T, Hess T, Heyman S, Kwiecien S, Konturek
SJ, Koziel J. Emerging role of fecal microbiota therapy in the treatment of
gastrointestinal and extra-gastrointestinal diseases. J Physiol Pharmacol. 2015
Aug;66(4):483-91.
Levkovich, T., Poutahidis, T., Smillie, C., Varian, B. J., Ibrahim, Y. M., Lakritz, J. R., … Erdman, S. E. (2013). Probiotic bacteria induce a “glow of health”. PloS One, 8(1), e53867. http://doi.org/10.1371/journal.pone.0053867
Ley, R. E., Turnbaugh, P. J., Klein, S., & Gordon, J. I. (2006). Microbial ecology: Human gut microbes associated with obesity. Nature, 444(7122), 1022–1023. http://doi.org/10.1038/4441022a
Lillford, P. J., Chen, J., Lillford, P., Lillford, P., Hutchings, J., Lillford, P., … Mithen, R. F. (2016). The impact of food structure on taste and digestibility. Food Funct., 23, 1. http://doi.org/10.1039/C5FO01375E
Louis S, Tappu R-M, Damms-Machado A, Huson DH, Bischoff SC. Characterization of the Gut Microbial Community of Obese Patients Following a Weight-Loss Intervention Using Whole Metagenome Shotgun Sequencing. Covasa M, ed. PLoS ONE. 2016;11(2):e0149564. doi:10.1371/journal.pone.0149564.
Lowry CA, Smith DG, Siebler PH, Schmidt D, Stamper CE, Hassell JE, Yamashita PS, Fox JH, Reber SO, Brenner LA, Hoisington AJ. The Microbiota, Immunoregulation, and Mental Health: Implications for Public Health. Current Environmental Health Reports. 2016 Sep 1;3(3):270-86.
Luo, Y., Chen, G.-L., Hannemann, N., Ipseiz, N., Krönke, G., Bäuerle, T., … Bozec, A. (2015). Microbiota from Obese Mice Regulate Hematopoietic Stem Cell Differentiation by Altering the Bone Niche. Cell Metabolism (Vol. 22).
Ly, N. P., Litonjua, A., Gold, D. R., & Celedón, J. C. (2011). Gut microbiota, probiotics, and vitamin D: Interrelated exposures influencing allergy, asthma, and obesity? The Journal of Allergy and Clinical Immunology, 1087–1094. http://doi.org/10.1016/j.jaci.2011.02.015
Ly, N. P., Litonjua, A., Gold, D. R., & Celedón, J. C. (2011). Gut microbiota, probiotics, and vitamin D: Interrelated exposures influencing allergy, asthma, and obesity? The Journal of Allergy and Clinical Immunology, 1087–1094. http://doi.org/10.1016/j.jaci.2011.02.015
Ma W, Rimm EB, Rexrode KM, Qi L. Associations of Bowel Movement Frequency with Risk of Coronary Heart Disease and Mortality Among US Women. Circulation. 2016 Mar 1;133(Suppl 1):AP080-.
Mayer, E. A., Knight, R., Mazmanian, S. K., Cryan, J. F., & Tillisch, K. (2014). Gut microbes and the brain: paradigm shift in neuroscience. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, 34(46), 15490–6. http://doi.org/10.1523/JNEUROSCI.3299-14.2014
Muñoz-Garach, A., Diaz-Perdigones, C., & Tinahones, F. J. (2016). Gut microbiota and type 2 diabetes mellitus. Endocrinologia Y
Nutricion : Organo de La Sociedad Espanola de Endocrinologia Y Nutricion. http://doi.org/10.1016/j.endonu.2016.07.008
Parthasarathy G, Chen J, Chen X, Chia N, O’Connor HM, Wolf PG, Gaskins HR, Bharucha AE. Relationship Between Microbiota of the Colonic
Mucosa vs Feces and Symptoms, Colonic Transit, and Methane Production in Female Patients With Chronic Constipation. Gastroenterology. 2016 Feb;150(2):367-79.e1. doi: 10.1053/j.gastro.2015.10.005. Epub 2015 Oct 13.
Parvaneh, K., Ebrahimi, M., Sabran, M. R., Karimi, G., Hwei, A. N. M., Abdul-Majeed, S., … Jamaluddin, R. (2015). Probiotics
(Bifidobacterium longum) Increase Bone Mass Density and Upregulate Sparc and Bmp-2 Genes in Rats with Bone Loss Resulting from
Ovariectomy. BioMed Research International, 2015, 897639. http://doi.org/10.1155/2015/897639
Poutahidis, T., Kleinewietfeld, M., Smillie, C., Levkovich, T., Perrotta, A., Bhela, S., … Erdman, S. E. (2013). Microbial reprogramming inhibits Western diet-associated obesity. PloS One, 8(7), e68596. http://doi.org/10.1371/journal.pone.0068596
Poutahidis, T., Springer, A., Levkovich, T., Qi, P., Varian, B. J., Lakritz, J. R., … Erdman, S. E. (2014). Probiotic microbes sustain youthful serum testosterone levels and testicular size in aging mice. PloS One, 9(1), e84877. http://doi.org/10.1371/journal.pone.0084877
Poutahidis, T., Springer, A., Levkovich, T., Qi, P., Varian, B. J., Lakritz, J. R., … Erdman, S. E. (2014). Probiotic microbes sustain youthful serum testosterone levels and testicular size in aging mice. PloS One, 9(1), e84877. http://doi.org/10.1371/journal.pone.0084877
Pusceddu, M. M., Kelly, P., Stanton, C., Cryan, J. F., & Dinan, T. G. (2016). N-3 Polyunsaturated Fatty Acids through the Lifespan: Implication for Psychopathology. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). http://doi.org/10.1093/ijnp/pyw078
Rao, A. V., Bested, A. C., Beaulne, T. M., Katzman, M. A., Iorio, C., Berardi, J. M., & Logan, A. C. (2009). A randomized, double-blind, placebo-controlled pilot study of a probiotic in emotional symptoms of chronic fatigue syndrome. Gut Pathogens, 1(1), 6. http://doi.org/10.1186/1757-4749-1-6
Reid, G. (2016). Can breast microbiota provide protective effects against cancer? Future Microbiology, 11, 987–9. http://doi.org/10.2217/fmb-2016-0138
Remely M, Tesar I, Hippe B, Gnauer S, Rust P, Haslberger AG. Gut microbiota composition correlates with changes in body fat content due to weight loss. Benef Microbes. 2015;6(4):431-9. doi: 10.3920/BM2014.0104. Epub 2015 Feb 12.
Ridaura, V., & Belkaid, Y. (2015). Gut Microbiota: The Link to Your Second Brain. Cell, 161(2), 193–194. http://doi.org/10.1016/j.cell.2015.03.033
Robertson, R. C., Seira Oriach, C., Murphy, K., Moloney, G. M., Cryan, J. F., Dinan, T. G., … Stanton, C. (2016). Omega-3 polyunsaturated fatty acids critically regulate behaviour and gut microbiota development in adolescence and adulthood. Brain, Behavior, and Immunity. http://doi.org/10.1016/j.bbi.2016.07.145
Sherwin, E., Rea, K., Dinan, T. G., & Cryan, J. F. (2016). A gut (microbiome) feeling about the brain. Current Opinion in Gastroenterology, 32(2), 96–102. http://doi.org/10.1097/MOG.0000000000000244
Sherwin, E., Sandhu, K. V, Dinan, T. G., & Cryan, J. F. (2016). May the Force Be With You: The Light and Dark Sides of the Microbiota-Gut-Brain Axis in Neuropsychiatry. CNS Drugs. http://doi.org/10.1007/s40263-016-0370-3
Shirouchi, B., Nagao, K., Umegatani, M., Shiraishi, A., Morita, Y., Kai, S., … Sato, M. (2016). Probiotic Lactobacillus gasseri SBT2055 improves glucose tolerance and reduces body weight gain in rats by stimulating energy expenditure. The British Journal of Nutrition, 116(3), 451–8. http://doi.org/10.1017/S0007114516002245
Sokol, H., Pigneur, B., Watterlot, L., Lakhdari, O., Bermúdez-Humarán, L. G., Gratadoux, J.-J., … Langella, P. (2008). Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proceedings of the National Academy of Sciences of the United States of America, 105(43), 16731–6. http://doi.org/10.1073/pnas.0804812105
Sokol, H., Pigneur, B., Watterlot, L., Lakhdari, O., Bermúdez-Humarán, L. G., Gratadoux, J.-J., … Langella, P. (2008). Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proceedings of the National Academy of Sciences of the United States of America, 105(43), 16731–6. http://doi.org/10.1073/pnas.0804812105
Spreadbury, I. (2012). Comparison with ancestral diets suggests dense acellular carbohydrates promote an inflammatory microbiota, and may be the primary dietary cause of leptin resistance and obesity. Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy, 5, 175–89. http://doi.org/10.2147/DMSO.S33473
Stilling, R. M., van de Wouw, M., Clarke, G., Stanton, C., Dinan, T. G., & Cryan, J. F. (2016). The neuropharmacology of butyrate: The bread and butter of the microbiota-gut-brain axis? Neurochemistry International, 99, 110–32. http://doi.org/10.1016/j.neuint.2016.06.011
Taba Taba Vakili S, Nezami BG, Shetty A, Chetty VK, Srinivasan S. Association of high dietary saturated fat intake and uncontrolled diabetes with constipation: Evidence from the National Health and Nutrition Examination Survey. Neurogastroenterology & Motility. 2015 Oct 1;27(10):1389-97.
Tap J, Furet JP, Bensaada M, Philippe C, Roth H, Rabot S, Lakhdari O, Lombard V, Henrissat B, Corthier G, Fontaine E, Doré J, Leclerc M. Gut microbiota richness promotes its stability upon increased dietary fibre intake in healthy adults. Environ Microbiol. 2015 Dec;17(12):4954-64. doi: 10.1111/1462-2920.13006. Epub 2015 Sep 3.
Taylor, M. W. (2016). Devil in the detail: A closer look at childhood obesity and the gut microbiota. Environmental Microbiology. http://doi.org/10.1111/1462-2920.13540
Urbaniak, C., Gloor, G. B., Brackstone, M., Scott, L., Tangney, M., & Reid, G. (2016). The Microbiota of Breast Tissue and Its Association with Breast Cancer. Applied and Environmental Microbiology, 82(16), 5039–48. http://doi.org/10.1128/AEM.01235-16
Vandeputte D, Falony G, Vieira-Silva S, Tito RY, Joossens M, Raes J. Stool consistency is strongly associated with gut microbiota richness and composition, enterotypes and bacterial growth rates. Gut. 2016 Jan;65(1):57-62. doi: 10.1136/gutjnl-2015-309618. Epub 2015 Jun 11.
Weir TL, Manter DK, Sheflin AM, Barnett BA, Heuberger AL, Ryan EP. Stool Microbiome and Metabolome Differences between Colorectal Cancer Patients and Healthy Adults. White BA, ed. PLoS ONE. 2013;8(8):e70803. doi:10.1371/journal.pone.0070803.
Wu GD, Chen J, Hoffmann C, et al. Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes. Science 2011;334(6052):105-108. doi:10.1126/science.1208344.
Yang X-Y, Chen Q-F, Li Y-P, Wu S-M. Mycobacterium vaccae as Adjuvant Therapy to Anti-Tuberculosis Chemotherapy in Never-Treated Tuberculosis Patients: A Meta-Analysis. Cardona P-J, ed. PLoS ONE. 2011;6(9):e23826. doi:10.1371/journal.pone.0023826.
Yiu, J. H. C., Dorweiler, B., & Woo, C. W. (2016). Interaction between gut microbiota and toll-like receptor: from immunity to metabolism. Journal of Molecular Medicine (Berlin, Germany). http://doi.org/10.1007/s00109-016-1474-4


If you have any questions, please do not hesitate to contact me. You can personally verify the products by ordering them right now. Attention, please: after pressing the button you will be redirected to the Coral Order system site.
The contents of this Web site are not intended to offer personal medical advice. You should seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this Web site. #ManufacturedGMPRegisteredFacility.

No comments: